yes get a good company and pay the price, I found so much dust and dirt and wood and paint chips and bugs and even bottle caps in my ductwork. I hired a major plumbing company who cleaned ductwork and i will say they did an excellent job cleaning my vent. they did miss one point in my ductwork because i still started to see dust all over my furniture and i realized that my retunduct work that was connected with a piece of sheet metal beam which was 16" across , the contractor that built my condo used a 16" wide sheet of sheet metal to connect the vent system to my return for the air to return back into my condo. The contractor should have built a 8" x16" square duct by 6 feet long to connect my intake to my return instead of using a sheet of sheet metal 16" wide by using two 3' sections by 16 inches wide. That was a shor cut which caused a major problem fir me.
Some research suggests that cleaning heating and cooling system components (e.g., cooling coils, fans and heat exchangers) may improve the efficiency of your system, resulting in a longer operating life, as well as some energy and maintenance cost savings. However, little evidence exists that cleaning only the ducts will improve the efficiency of the system.